BIH Lecture: Hans-Peter Kiem

Lecture 25: "Novel Approaches To Targeting Hematopoietic Stem Cells for Ex Vivo and in Vivo Gene Therapy" "

In the BIH Lecture on 16 September 2022, the world-renowned expert in stem cell gene therapy, Prof. Hans-Peter Kiem, talked about HSC gene therapy and addressed current limitations his team encountered regarding HSC characterization, engraftement and targeting. The goal of the Kiem Lab is to develop better stem cell transplantation and cell and gene therapy treatments for patients with genetic, infectious, and malignant diseases. In his talk, Kiem focused on gene editing approaches and disease applications. He explained that many diseases could be treated with HSC gene therapy but the largest population are patients with sickle cell disease, thalassemia or HIV and the highest incidents regarding mortality are in located in low and middle-income countries. So the Kiem lab works on how to make gene therapy more accessible and potentially be able to move them to the beforementioned settings.

The lecture was moderated by Prof. Christopher Baum (BIH) and followed by a Meet the Speaker-session, led by Dr. Stefanie Seltmann (BIH).

Further information on this BIH Lecture:
https://www.bihealth.org/en/notices/b...

About the Speaker:
https://www.fredhutch.org/en/faculty-...

Further information on the BIH Lecture Series "Frontiers in Translational Medicine - Scientific and Structural Challenges":
https://www.bihealth.org/en/news/even...