Скачать или смотреть Revolutionary Reprogramming: How Scientists Transform Skin into Neurons Without Stem Cells

Scientists have achieved a revolutionary breakthrough in cellular reprogramming using neurogenins and transcription factors to convert skin cells directly into neurons at unprecedented efficiency. MIT researchers identified NGN2, ISL1, and LHX3 as the key players that completely rewire cellular identity. This technology could transform treatment for the 50+ million people with neurodegenerative diseases worldwide.

⏱️Timeline
00:00 - Introduction
01:15 - The Science of Cellular Reprogramming
03:00 - Technological Advancements
04:20 - Medical Applications
05:10 - Challenges and Future Outlook

🧪 RESEARCH SOURCES:
MIT Research Papers:
‣ “Compact transcription factor cassettes generate functional motor neurons”
(Cell Systems, March 2025) [MIT News Article]
‣ “Proliferation history drives direct neural conversion”
(Gallaway et al., 2025)

News Coverage:
‣ [Earth.com](http://earth.com/): “2025 Neuron Reprogramming Revolution”
(March 18, 2025)
‣ GEN News: “High-Efficiency Cell Conversion Method”

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#Neurogenins #Science #Technology #Reprogramming #Neurons #GeneTherapy #CellBiology #Biotechnology #ALS #ParkinsonsDisease