Скачать или смотреть Ticarcillin + Clavulanic acid; Chemical name, Molecular Formula, Molar mass, Chemical Structure

🔬 Chemical Details
Ticarcillin
Chemical name (IUPAC):
(2S,5R,6R)-6-

\[(carboxyphenyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo

\[3.2.0]heptane-2-carboxylic acid

Molecular formula:
C₁₅H₁₆N₂O₆S

Molar mass:
≈ 384.37 g/mol

Structure description:

A β-lactam ring fused to a thiazolidine ring (typical of penicillins).

A carboxyphenyl side chain that broadens antibacterial spectrum.

Multiple stereocenters ensuring proper binding to bacterial enzymes.

Clavulanic acid
Chemical name (IUPAC):
(2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo

\[3.2.0]heptane-2-carboxylic acid

Molecular formula:
C₈H₉NO₅

Molar mass:
≈ 199.16 g/mol

Structure description:

A β-lactam ring fused to an oxazolidine ring.

A hydroxyethylidene substituent at position 3.

Functions as a β-lactamase inhibitor, protecting ticarcillin from enzymatic degradation.

⚗️ Combination Significance
Ticarcillin: A broad-spectrum penicillin effective against Gram-negative bacteria.

Clavulanic acid: Prevents bacterial β-lactamases from breaking down ticarcillin.

Together: The combination extends antibacterial activity and is used clinically for resistant infections

#Ticarcillin #Clavulanicacid