Скачать или смотреть Zacin (Capsaicin) Cream

Zacin cream contains the active ingredient capsaicin, which is the substance found naturally in red chilli peppers that gives them their heat. The cream is applied to the skin to relieve pain associated with osteoarthritis.
Capsaicin works by desensitising nerve cells to pain. It does this by binding to sensory receptors called nociceptors that are found at the end of the nerves. When stimulated, these receptors normally send nerve signals to the spinal cord and brain that result in the perception of pain. When capsaicin binds to these pain receptors it initially causes a painful burning sensation. However, with continued application of the capsaicin, the pain receptors become overloaded and desensitised and this makes them less responsive to painful stimulation.