Vasculitis | Causes, Symptoms & Treatment

Vasculitis | Causes, Symptoms & Treatment

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

Vasculitis is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and resultant damage. Although both occur in vasculitis, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities.

Signs and symptoms
Possible signs and symptoms include:

General symptoms: fever, unintentional weight loss, tiredness
Skin: palpable purpura, livedo reticularis
Muscles and joints: muscle pain or inflammation, joint pain or joint swelling
Nervous system: mononeuritis multiplex, headache, stroke, tinnitus, reduced visual acuity, acute visual loss
Heart and arteries: heart attack, high blood pressure, gangrene, heart palpitations
Respiratory tract: nosebleeds, bloody cough, lung infiltrates
GI tract: abdominal pain, bloody stool, perforations (hole in the GI tract)
Kidneys: inflammation of the kidney's filtration units (glomeruli)
Ear and Nose: sinus infections, ear infections, and hearing loss
Causes
There are several different etiologies for vasculitides. Although infections usually involve vessels as a component of more extensive tissue damage, they can also directly or indirectly cause vasculitic syndromes through immune-mediated secondary events. Simple vascular thrombosis usually only affects the luminal process, but through the process of thrombus organization, it can also occasionally cause a more chronic vasculitic syndrome. The autoimmune etiologies, a particular family of diseases characterized by dysregulated immune responses that produce particular pathophysiologic signs and symptoms, are more prevalent.
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