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Fingerprint Chromatography

Fingerprint chromatography is a technique used mainly in the analysis of complex mixtures, such as herbal medicines, food products, or pharmaceuticals, to create a chemical "fingerprint" — a unique chromatographic profile that can help:

Identify components in a mixture

Authenticate materials

Ensure quality control

Detect adulteration or contamination


This "fingerprint" is obtained using chromatographic techniques like:

HPLC (High-Performance Liquid Chromatography)

GC (Gas Chromatography)

TLC (Thin Layer Chromatography)


Chemometrics + Fingerprint Chromatography

When combined with chemometrics (mathematical and statistical analysis of chemical data), the data from chromatography can be interpreted more powerfully. This is used for:

Classifying samples

Pattern recognition

Quantitative prediction

Quality assurance in herbal or pharmaceutical products


Example Use: Identifying whether two herbal extracts are from the same species by comparing their chromatographic fingerprints using statistical tools like PCA (Principal Component Analysis).
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#Chemometrics

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#HPLC

#TLC

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#Phytochemistry

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#PharmaceuticalAnalysis

#FoodAuthentication

#AnalyticalChemistry

#PCA

#MultivariateAnalysis

#NaturalProductAnalysis