Скачать или смотреть Explained: The Hallmarks of Cancer – How Hanahan & Weinberg Revolutionised Oncology

Unlock the foundational framework of modern cancer biology! In this video, we break down the seminal paper "The Hallmarks of Cancer" (Hanahan & Weinberg, 2000) – a landmark publication that defined six core biological capabilities driving tumor development.

🔬 What You’ll Learn:

The 6 original hallmarks of cancer:
1) Sustaining proliferative signalling
2) Evading growth suppressors
3) Resisting cell death
4) Enabling replicative immortality
5) Inducing angiogenesis
6) Activating invasion and metastasis
How this framework unified oncology research.
Its impact on targeted therapies and diagnostics.
The updated hallmarks (2011) including metabolic reprogramming and immune evasion.

📄 Critical Citations & Attribution:

Original Paper:
Hanahan, D., & Weinberg, R. A. (2000). The Hallmarks of Cancer. Cell, 100(1), 57–70.
DOI: 10.1016/S0092-8674(00)81683-9
Updated Review (2011):
Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of Cancer: The Next Generation. Cell, 144(5), 646–674.
DOI: 10.1016/j.cell.2011.02.013

📚 Disclaimer:
This video is created for educational purposes only and does not reproduce the full content of the original article. All concepts are presented in simplified terms, with original work appropriately cited. This is not a substitute for professional medical or academic advice.

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