Скачать или смотреть Artificial Brain Simulation - Thalamocortical System, 3.5 Billion Synapses, 16.7 Million Neurons

Download DigiCortex demo here: http://www.digicortex.net

SpikeFun 0.90 simulation of the mammalian brain's thalamocortical system with 16.7 million neurons and approx. 3.5 billion synapses (modeled using Izhikevich phenomenological neuron model with multiple compartments).

Total simulation memory usage is 350 GB. Network build-up took approx. 2 hours on dual-CPU 16 core Intel Xeon 2687W system running @3.1 GHz.

Simulation models AMPA, NMDA and GABA synaptic receptor kinetics, depressing and facilitating synapses (including differential axonal signalling depending on the target post-synaptic type), myelinated and non-myelinated axons, axonal bifurcations as well as short term synaptic plasticity modeled with Tsodyks-Markram quantal model of synaptic transmission as well as long term synaptic plasticity which is modeled using phenomenological model of spike-timing dependent plasticity (STDP).

Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.

All neurons have multiple compartments. Pyramidal neurons have basal dendritic sub-tree as well as apical tuft that bifurcates in at least two dendritic branches in the terminating cortical layer.

Average number of synapses per neuron is ~210, ranging from ~80 for basket cells of cortical layer II to ~380 for the pyramidal cells of cortical layer V which project to layers V and VI, identified as p5(L5/6) in the simulation.

During the simulation, multiple activity clusters could be observed. Simulated intracortical EEG near the end of the video shows desynchronized activity across different cortical regions.