Risk Factors of drug - drug interactions

Описание к видео Risk Factors of drug - drug interactions

Risk factors for drug-drug interactions (DDIs) include:

1. Polypharmacy (taking multiple medications)
2. Age (elderly or pediatric populations)
3. Liver or kidney disease
4. Metabolic disorders (e.g., diabetes)
5. Genetic predisposition
6. Certain medications (e.g., warfarin, digoxin, lithium)
7. High doses or prolonged treatment
8. Multiple prescribers or pharmacies
9. Changes in medication regimen
10. Lack of medication reconciliation
11. Patient nonadherence
12. Drug metabolism (e.g., CYP450 enzymes)
13. Drug transport (e.g., P-glycoprotein)
14. Inhibition or induction of enzymes/transporters
15. Pharmacokinetic or pharmacodynamic interactions

To minimize DDIs, healthcare professionals should:

1. Conduct thorough medication reviews
2. Use drug interaction software/tools
3. Monitor patients closely
4. Adjust doses or medications as needed
5. Educate patients about potential interactions
6. Encourage open communication about medications

Remember, DDIs can be preventable with proper awareness and management!

#Druginteractions #Drugdruginteraction

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