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Introduction about semen analysis male infertility azoospermia cryptozoospermia testicular biopsy TESA TESE PESA, micro TESA all about embryology embryo development lab setup...

Testicular Sperm Aspiration (TESA) is performed by inserting a needle into the testis to aspirate fluid and tissue. The aspirated tissue is then processed in the embryology laboratory.

Percutaneous Epididymal Sperm Aspiration (PESA) does not require a surgical incision. A needle is passed directly to the head of the epididymis to aspirate fluid. The sperm cells are retrieved from the fluid and the embryologist prepares them for ICSI.

Azoospermia means zero sperm count or nil sperm count, which needs to be proven in two successive reports, which are done approximately 4-6 weeks apart.

Types of Azoospermia
-Non-obstructive azoospermia
-Obstructive azoospermia

Male reproductive system
Before understanding what causes this obstruction lets understand the male reproductive system
1. Testes, commonly known as testicles, are the part of the male reproductive organ where sperms are produced.
2. Later these sperms travel via a duct or a pipeline called the vas deference and are temporarily stored in seminal vesicles.
3. In the seminal vesicles, certain nutrition and fluids are added to these sperms.
4. At the time of intercourse, the sperms are ejaculated through ejaculatory ducts from the penis and it gets out as the seminal fluid.
In the case of obstructive azoospermia, there is a blockage in the epididymis or vas deference or elsewhere along the reproductive tract.

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Non-obstructive azoospermia (NOA): there is no blockage in the reproductive tract but there is some abnormality in the testes which causes a reduction in sperm production.
Causes of Non-obstructive azoospermia (NOA)
1. Congenital Issues with tests. i.e. Chryptorchidism, Retractile Testes
2. Injury to the testes
3. Viral Infections in Childhood
4. Endocrinological problems related to the brain and secretion of hormones in the body.
5. Gonadotoxic therapy. i.e, therapies that affect the gonadotropin hormones in the body.

Obstructive Azoospermia: The testes are normal but the sperm produced somehow can not come out due to the blockage or absence of the duct. This is obstructive azoospermia.
Causes of Obstructive Azoospermia
1. The obstruction could be because of genital infections that block the vas deference.
2. Blockage of ejaculatory ducts.
3. In some rare cases, there can congenital absence of this duct which is no as Congenital Bilateral Absence Of Vas Deference.

Let us try to know that Is it possible to cure azoospermia naturally?
-In a practical scenario, there is no existence of such kind of medicine or therapy which can give demonstrable and instant results in Obstructive Azoospermia & Non-Obstructive Azoospermia.
-In a rare situation, the doctors can give a prolonged injection for 2-3 years and it might enhance the sperm count.
-But with medication and dietary changes, it's not possible to cure Azoospermia.
-Patients with Azoospermia can have a child with their own sperm as long as they take correct treatment i.e TEFNA or Micro-Dissection.

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