Скачать или смотреть #11 Linkage and QTL mapping in outcrossing species

Today's episode provides a detailed look into the methods and challenges of genetic analysis in outcrossing plant species, which cannot easily produce inbred lines. We highlight that these species, like trees and certain fruits, present unique complexities due to traits like long juvenile periods and self-incompatibility. We explain historical techniques, such as the double pseudo-testcross strategy for linkage mapping, while emphasizing the benefits of more modern approaches like simultaneous linkage map integration using software like OneMap. The discussion also covers composite interval mapping (CIM) for identifying quantitative trait loci (QTLs) in these complex populations, outlining the underlying genetic models and statistical methods for detecting and characterizing these genetic regions.