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Show Notes: Long Covid, Immune Dysregulation, and Spike Protein with Dr. Paul Anderson
Episode Overview

Dr. Kasey Holland interviews Dr. Paul Anderson, a recognized expert in integrative and naturopathic medicine, about his research on long COVID, spike protein pathology, and treatment approaches.

Timestamps & Topics

[0:45] - Introduction & Dr. Anderson's Background

Dr. Anderson's credentials and experience
Focus on complex infectious, chronic, and oncologic illness
Background in IV therapies and cancer research

[2:54] - How Dr. Anderson Got Into COVID Research

Early observations of post-COVID syndrome
Similarities to other chronic infectious illnesses
Pattern recognition from previous infections

[6:39] - Comparing COVID to Other Infections

Similarities to Epstein-Barr virus and cytomegalovirus
Lyme disease and immune shifting patterns
Furin cleavage sites and immune disruption

[11:15] - Understanding Immune Dysregulation

Why COVID creates prolonged inflammation
The missing "resolution phase" in immune response
How this differs from typical influenza recovery

[11:44] - Spike Protein Explained

Spike protein from infection vs. vaccination
How spike protein affects the immune system
Duration of spike protein presence in the body

[18:19] - Defining Long COVID Symptoms

Wide variety of individual presentations
Importance of testing for spike protein levels

[19:30] - Testing for Long COVID

SARS-CoV-2 [S - protein] semi-quantitative total antibody spike test
Understanding test results (hundreds vs. thousands)
Available through LabCorp

[25:17] - Baseline Health Markers

Importance of comprehensive testing
Hormonal, liver, kidney function assessment
Looking at overall health beyond spike protein

[27:15] - Treatment Approaches for Spike Protein

Two main pathways: blocking/binding and degradation
Combination of drug and natural therapies

[31:36] - Blocking and Binding Therapies

Ivermectin as immunomodulatory agent
Natural options: quercetin, curcumin, flavonoids
Milk thistle for liver protection and anti-inflammatory effects

[33:30] - Degrading Spike Protein

Enzyme therapy with nattokinase
Dual benefit: reducing clotting and breaking down spike protein
Addressing micro-clot formation

[35:38] - Advanced Treatment: Plasmapheresis

Total plasma exchange (TPE) explained
How the procedure works
When to consider this intensive therapy

[39:29] - Plasmapheresis Process Details

Cell separation and plasma removal
Albumin replacement
Treatment intervals (4-8 weeks between sessions)
Growing availability of outpatient centers

[41:01] - Alternative: Plasma Donation

Less intensive option than full plasmapheresis
Repeated donations can lower toxin/protein levels
Study in firefighters showing effectiveness

[44:12] - Treatment Experience and Recovery

First two treatments are most intense
Importance of supportive therapies between sessions
Antioxidant support and nutrition

[44:32] - Final Thoughts and Resources

Importance of baseline testing
Escalating treatment approach
Hope for recovery with proper treatment
Dr. Anderson's YouTube channel and webinar series

[48:43] - Closing Remarks

Key Takeaways
Long COVID involves immune dysregulation and spike protein persistence
Testing is crucial: SARS-CoV-2 S- Protein semi-quantitative antibody test
Treatment requires addressing both spike protein AND comorbidities
Multiple treatment options available from natural therapies to advanced plasmapheresis
Recovery is possible but requires comprehensive, escalating approach
Resources Mentioned
Dr. Anderson's research paper (139 references)
YouTube channel for patient education
Monthly webinar series for healthcare providers
Plasmapheresis centers (search: "TPE plasma")
Dr. Paul Anderson's paper on Long Covid 

A comprehensive review of definitions, pathogenesis, diagnostics, and evidence-based therapeutic approaches for managing Long-COVID and post-vaccination syndromes in clinical practice.

SARS-CoV-2 Semi-Quantitative Total Antibody, Spike [S-Protein, Semi-quant]

LabCorp Testing

Quest DIagnostics Testing

Boston Heart Diagnostics Testing

Therapeutic Plasma Exchange (TPE) Locations
Dr. Paul Anderson Educational YouTube Channel
Dr. Kasy Holland Website