Myasthenia Gravis (MG) - Muscle weakness & Fatigue - Causes, Symptoms, Diagnosis, Treatment - Neuro

Myasthenia Gravis (MG) - Muscle weakness and Fatigue - Causes, Symptoms, Diagnosis, Treatment. Myasthenia gravis is a neuromuscular disease (autoimmune disease) characterized by the presence of anti-acetylcholine receptor antibodies targeting the nicotinic receptors on the skeletal muscle surface at the neuromuscular junction (NMJ) or motor end plate. This is different from Lambert-Eaton myasthenic syndrome (LEMS). Myasthenia causes muscle weakness that worsens with use, especially at distal muscles, extraocular muscles (EOMs) & respiratory muscles. Myasthenia is associated with thymoma. EMG and challenge tests can help with the diagnosis. Treated with pyridostigmine.

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