Скачать или смотреть Tapemark's Dissolution Testing Process

Chemist Paul Zackery discusses the analytical testing services that we provide onsite here at Tapemark. Learn more about our in-house analytical lab: https://www.tapemark.com/services/ana...

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Transcript:

I'm Paul Zachary, a chemist here at Tapemark. I'm gonna talk a little bit today about the dissolution capabilities that we have onsite. Dissolution is an important test that we use to determine the correlation between in vivo and in vitro testing. The dissolution apparatus provides an in vitro correlation to bioavailability studies performed at our clinics. The capabilities at Tapemark include apparatus one which is the rotating basket, apparatus two which is a rotating paddle, apparatus five which is a rotating paddle over a disc, and apparatus six which is a rotating cylinder.

We have two configurations to allow for the different sizes in our transdermal patches. We also have the capabilities for an apparatus 7, it's a newer form of reciprocating cylinder that allows for better analysis for transdermal parts. We employ a number of different ways to account for our different size parts as transdermal films, transdermal patches, and buccal films. The smaller cylinders are typically used for our buccal film products in the smaller baskets. We also have capabilities to run larger samples and are in a more typical larger vessel. Our apparatuses are also equipped with autosamplers, if necessary, we can also perform it manually by pulling through a canal.