Скачать или смотреть Economic-Strengthening Interventions to address HIV Risk and Treatment: Kenya and Malawi

Economic-Strengthening Interventions to address HIV Risk and Treatment Outcomes: Two newly-funded clinical trials in Kenya and Malawi .

Amy Conroy, PhD Associate Professor of Medicine, UCSF and Jennifer Velloza, PhD Assistant Professor of Epidemiology and Biostatistics, UCSF.

Mlambe: An Economic and Relationship-Strengthening Intervention for Unhealthy Drinking in Couples Living with HIV in Malawi: Unhealthy alcohol use has been described as adding “fuel to the fire” of the HIV epidemic in Sub-Saharan Africa, and is a major barrier to treatment adherence. Key drivers of unhealthy drinking are unemployment and poverty, yet few interventions have targeted the economic determinants of alcohol use. Dr. Conroy will describe the development of a novel economic and relationship-strengthening intervention for unhealthy alcohol use with couples in Malawi (Mlambe), and pilot trial findings on feasibility, acceptability, and effects on health. A full scale RCT is now underway to test the efficacy and cost-effectiveness of Mlambe.

Dr. Amy Conroy is an Associate Professor within the Center for AIDS Prevention Studies and Division of Prevention Sciences. She is a behavioral scientist with over a decade of experience conducting dyadic research with heterosexual couples at risk and living with HIV in Malawi, South Africa, and Kenya. Her research is grounded in theory from the field of relationship science, and employs mixed-methods and dyadic analysis techniques to understand couple-level health behavior. Dr. Conroy is currently leading three programs of research – all with couples—to develop and test a range of behavioral interventions for cardiometabolic disorders, unhealthy alcohol use, and perinatal depression in southern Africa with diverse funding from the NIMH, NIAAA, and NHLBI.

Vijana Shamba: A School-based Intervention to Address Food Insecurity, Mental Health, and Sexual Health Outcomes for Young Women in Kenya: The incidence of HIV and STIs remains high among adolescent girls and young women in Western Kenya, driven by upstream structural factors like food insecurity and poverty which are worsened by extreme weather events. Dr. Velloza will describe plans for a new cluster randomized trial seeking to test the impact of an innovative climate-adaptive, school- and household-based intervention package (Vijana Shamba) on STI and HIV prevention outcomes. This work will be conducted with 800 adolescent girls and their caregivers in Western Kenya over the next five years and may provide a model for a multi-pronged approach to halt the cycle of extreme weather events, food insecurity, and poor sexual and reproductive health outcomes among young women.

Dr. Jennifer Velloza is an Assistant Professor in Residence in the Department of Epidemiology & Biostatistics and Co-Director of the UCSF Partnerships for Research in Implementation Science for Equity (PRISE) Center. She is also core faculty with the CAPS Implementation Science & Health Systems Core. Her research, teaching, and mentoring focus on advancing the field of HIV and STI prevention and the intersection with global mental health, specifically for adolescent girls and young women. She has conducted partnered implementation science and behavioral science research in Kenya and South Africa for over a decade, primarily funded by NIMH. Dr. Velloza also regularly leads implementation science training and capacity-building activities locally and globally.

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This presentation is hosted by CAPS/DPS/PRC Town Hall and the CAPS Developmental Core. Town Hall Chairs: Parya Saberi, PharmD and John Sauceda, PhD, MSc, CAPS Dev Core Co-Directors. Co-Sponsored by the CAPS Implementation Science and Health Systems (IS/HS) Core.

Recorded Tuesday, December 3rd, 2024.

0:00 Introductions
1:53 Mlambe: An Economic and Relationship Strengthening Intervention
6:52 Objects of the Mlambe Study
15:20 Preliminary Efficacy: Financial Behaviors
20:07 Conclusions
22:09 Full-Scale Efficacy Trial Underway
25:24 Vijana Shamba A School-based Intervention Young Women in Kenya
29:17 Shamba Maisha - Farming for Life
32:26 Study Design
37:59 Quantitative Findings
42:05 Vijana Shamba
46:06 Specific Aims
50:09 Q & A