Erythroblastosis Fetalis | Pathophysiology 🩺

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Erythroblastosis Fetalis | Pathophysiology 🩺

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

00:00:00 Rh negative mother and Rh positive baby in 1st pregnancy and its consequence
00:02:32 Rh negative mother and Rh positive baby in 2nd pregnancy and its consequence
00:03:52 Rh negative mother and Rh positive baby in 3rd pregnancy and its consequence
00:06:00 Rh negative mother and Rh positive baby in 4th pregnancy and its consequence
00:08:08 Difference in Hematopoiesis of liver, spleen and bone marrow
00:09:09 Erythroblastosis Fetalis
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Erythroblastosis fetalis is hemolytic anemia in the fetus caused by transplacental transmission of maternal antibodies to fetal red blood cells, usually due to incompatibility between maternal and fetal blood groups, often Rho(D) antigens.
Screen all pregnant women for blood type, Rh type, anti-Rho(D), and other antibodies that can cause erythroblastosis fetalis.
Give women at risk of sensitization Rho(D) immune globulin at 28 weeks gestation, within 72 hours of pregnancy termination, after any episode of vaginal bleeding during pregnancy, and after amniocentesis or chorionic villus sampling.
If women are at risk, periodically measure antibody levels and, if needed, middle cerebral artery blood flow.
Treat erythroblastosis fetalis with intrauterine fetal blood transfusions as needed and, if severe fetal anemia is detected, delivery at 32 to 35 weeks, depending on the clinical situation.
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