Скачать или смотреть Guest Lecture: Adel Francis - Polymer-Ceramic Composite Coatings on Biodegradable Magnesium

Polymer-Ceramic Composite Coatings on Biodegradable Magnesium for Biomedical Implants

25.10.2022 @ CY Advanced Studies I CY Cergy Paris Université

Biodegradable Magnesium is a significant and fascinating alternative to permanent metallic implants (e.g. stainless steel, titanium alloys, etc.) for orthopedic and dental applications. However, the vulnerability of magnesium to corrosion under physiological conditions has limited its introduction for therapeutic and clinical applications. Therefore, coating of magnesium seems to be a promising approach as it not only enables improvement in corrosion resistance but also provides a suitable surface for better bone bonding and cell growth. A novel candidate material for developing protective coatings on magnesium substrates is preceramic organosilicon polymers (POP). The interdisciplinary nature of organosilicon polymers and their molecular structures, as well as their diversity of applications have resulted in an unprecedented range of devices and synergies cutting across unrelated fields in biology and engineering. This project explores the surface modification of magnesium substrates by using a corrosion resistant coating made of polysiloxanes (polysilazanes)/bioactive glass (BG) composites (in the presence of other additives, e.g. chitosan) via different coating techniques, followed by thermal treatment at the temperature range of 260- 350°C under controlled atmosphere. Cell experiments to assess cell activity and ability of these two composite coatings by culturing MC3T3 and fibroblastic cells. Development of new corrosion resistant coatings is expected to open up a new era in the engineering of materials for medicine and especially for orthopedic and dental applications.

Adel Francis is Professor of Ceramics at Central Metallurgical R&D Institute (CMRDI) in Cairo. He is currently Fellows-in-Residence at CY AS, invited by ERRMECe laboratory.