New potential treatment could cure diabetes - Dr. Joe Zhou, Weill Cornell Medicine

We speak with Dr. Joe Zhou, Professor at Weill Cornell Medicine. In this podcast, Dr. Zhou talks about a major breakthrough that could potentially cure insulin induced diabetes using stem cells. In the preclinical work, the potential treatment reversed diabetes in mice.

Link to research: https://www.nature.com/articles/s4155...

0:00- Introduction
2:05- goal of developing new autologous therapy to treat most severe form of diabetic patients
3:30- importance of beta cells
6:16- glucose control is not effective for severe types of diabetes
7:00- effectiveness of today's current day diabetes treatment
9:50- therapeutic targets for finding a treatment
10:40- overview of the preclinical study for using autologous stem cells for diabetes
13:16- before & after results of the new cells when used in the animal models
17:47- how was the treatment injected in the mice
19:33- how were they able to derive the cells from the stomach for the use of treatment on mice
21:25- what was the ultimate importance of this study/what did we conclude from this study
22:17- what work is needed to move this to the next steps
25:18- what is the biggest obstacle in moving this forward
26:22- how soon could this be available for a clinical setting and for humans
29:14- how would this look like if used in a clinical setting? How often would it be used, how would it be injected, etc.?
32:00- what kind of support can we see from insurance for a treatment like this
34:10- how could this impact the future of treatment of other diseases
36:00- finishing thoughts

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