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While histamine intolerance is on the milder to moderate side of the mast cell disorder spectrum, mastocytosis is the most severe form of mast cell issues.
Unlike mast cell activation syndrome (MCAS), mast cell mastocytosis is often overlooked, taking patients nearly a decade to get diagnosed.
Symptoms often span multiple organs and can include skin rashes, gastrointestinal distress, and life-threatening anaphylaxis.
Often, mastocytosis patients have failed trialing very strict low-histamine diets, antihistamine medications, supplements for histamine intolerance, and other lifestyle changes.
Their quality of life is severely compromised and they have great difficulty leading any semblance of a normal life.
To dive into all things mast cell, including histamine intolerance, MCAS, and especially mastocytosis, I’m joined by Dr. Mariana Castells, M.D., Ph.D., a physician and researcher at Brigham and Women's Hospital with over 30 years of experience in allergy and immunology.
She is Director of the Mastocytosis Center, one of the few nationally and internationally recognized centers of excellence providing diagnosis, management, and treatment options for patients with mastocytosis and mast cell activation disorders.
LINKS DISCUSSED IN THIS EPISODE:
• Work with me - http://bit.ly/workwithme-yt
• FREE Stop My Skin Rashes Now eGuide - https://bit.ly/stopmyrashes-yt
• Find Dr. Castells online - https://physiciandirectory.brighamand...
• Healthy Skin Show ep. 265: Problem with Antihistamines That No One Tells You - https://www.skinterrupt.com/265
• Healthy Skin Show ep. 319: Mast Cell Activation Syndrome: What is MCAS + Why It's So Devastating - https://www.skinterrupt.com/319
• Healthy Skin Show ep. 378: If You’re Highly Sensitive (How Mast Cell Activation Diseases Make You Super Reactive) - https://www.skinterrupt.com/378
• Mast Cell Current Diagnostic Criteria (Consensus-2) - https://www.degruyter.com/document/do...
IN THIS EPISODE:
00:00 Introduction
02:02 What is mastocytosis versus MCAS?
07:16 Possible triggers of mast cell issues like MCAS and mastocytosis
10:09 Difference between histamine intolerance, MCAS, and mastocytosis
13:49 What is tryptase?
18:51 Problem testing histamine levels and issues with a low histamine diet
33:17 Can mast cell stabilizing medications help?
37:11 Final thoughts
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ABOUT JENNIFER FUGO, MS, CNS:
Jennifer Fugo, MS, LDN, CNS is a clinical nutritionist empowering adults who’ve been failed by conventional medicine to beat chronic skin and unending gut challenges. Because she’s overcome a long history of gut issues and eczema, Jennifer has empathy and insight to help her clients discover missing pieces and create doable integrative plans.
She holds a Master’s degree in Human Nutrition from the University of Bridgeport and is a Licensed Dietitian-Nutritionist and Certified Nutrition Specialist, and is the host of the Healthy Skin Show.
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DISCLAIMER: Jennifer Fugo is a clinical nutritionist who offers health, wellness + nutritional information for educational purposes only. You should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis, or treatment. It also does not create a client-practitioner relationship between yourself + Jennifer. If you have any concerns or questions about your health, you should consult with a physician or other healthcare professional first before making any changes. Do not disregard, avoid, or delay obtaining medical or health-related advice because of something you may have seen in these videos.
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#mastocytosis #mcas #mastcelldisorder
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