Episode 44 - Multi-system Inflammatory Syndrome in Children (MIS-C): An Interview with Dr. Ilene ...

 



EMplify June 2020



Multi-system Inflammatory Syndrome in Children (MIS-C) with COVID-19: An Interview with Dr. Ilene Claudius and Dr. Mohsen Saidinejad.




• What is it and when did we discover it as an entity?


• Have either of you treated anyone with the disease?


• Discussion of different cohorts of patients with MIS-C.


• Definition of MIS-C.


• Shock: cardiogenic and distributive shock presentations.


• Fever, is 4 days required?


• Discussion of where in the COVID-19 illness MIS-C occurs.


• Is clinical shock a requirement?


• Screening criteria (labs) and the Children’s Hospital Of Philadelphia pathway.


• What is available as treatment?



• A discussion of IVIG


• Steroids


• Cytokine blockers


• Remdesivir





• Why IVIG?


• Complications of the disease.


• Why are there more cases in New York?


• How has MIS-C changed your practice of testing children?


• Is there utility in testing for COVID-19 infection or antibodies in these cases?




 



Resources:
EB Medicine Novel 2019 Coronavirus SARS-CoV-2 (COVID-19): An Updated Overview for Emergency Clinicians (https://www.ebmedicine.net/topics/inf...)



EB Medicine COVID-19: The Impact on Pediatric Emergency Care (https://www.ebmedicine.net/topics/inf...)



Children’s Hospital of Philadelphia Clinical Pathway for MIS-C. (https://www.chop.edu/clinical-pathway...)



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