Скачать или смотреть Acute Inflammation Chemical Mediators: Plasma vs. Cell-Derived (Kinins, Histamine, Prostaglandins)

Quiz Question: Which of the following is a plasma-derived chemical mediator of acute inflammation?

A. Histamine

B. Prostaglandins

C. Cytokines

D. Kinins

THE CORRECT ANSWER is (D) Kinins!

Kinins, particularly bradykinin, are plasma-derived mediators. They circulate in the blood as inactive precursors (like Hageman factor-dependent factors) and are activated by the coagulation cascade during injury.

Key Functions of Kinins:

Pain: Bradykinin is a powerful mediator of pain.

Vasodilation: Causes dilation of arterioles.

Increased Vascular Permeability: Leads to edema (swelling).

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