Personalised Treatment Trials: Monitoring and Improving the Connection of Treatments to Patients

The Melbourne ME/CFS Collaboration is conducting a study to closely watch how different treatments affect ME/CFS and Long COVID patients, using a very tailored approach. The team will collect samples from patients before, during, and after their treatment to see what biological changes happen and how these relate to whether they feel better or not. This method will help the researchers figure out which treatments work, why they work, and who they work best for.

The team plans to study 200 patients over three years. Each patient will be part of the study for about 3 to 4 months, during which they will try 2 to 3 different treatments. This includes three visits to the clinic and involves analysing many samples they provide, like blood and urine. This large collection of data from all the patients will help the researchers make better predictions about which treatments are most likely to help others in the future.

Watch this video to learn more about this study from Chris Armstrong, PhD, Director of the Melbourne ME/CFS Collaboration.