Structure of a skeletal muscle - Muscle Physiology Animations || USMLE videos

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Structure of a skeletal muscle - Muscle Physiology Animations

Structure of Skeletal Muscle
A whole skeletal muscle is considered an organ of the muscular system. Each organ or muscle consists of skeletal muscle tissue, connective tissue, nerve tissue, and blood or vascular tissue.

Skeletal muscles vary considerably in size, shape, and arrangement of fibers. They range from extremely tiny strands such as the stapedium muscle of the middle ear to large masses such as the muscles of the thigh. Some skeletal muscles are broad in shape and some narrow. In some muscles the fibers are parallel to the long axis of the muscle; in some they converge to a narrow attachment; and in some they are oblique.

Skeletal muscle is composed of bundles of elongated muscle fibres which are cylindrical and multinucleated. Fibres show a characteristic banding pattern with cross-striations of alternating light and dark bands. The light bands are divided by a Z disc (dark transverse line). The functional subunit is known as the sarcomere, and this extends between two Z discs.

Muscle fibres are surrounded by supportive layers of connective tissue:

Endomysium – surrounds individual muscle fibres
Perimysium – surrounds a bundle of muscle fibres, forming a fascicle (functional unit)
Epimysium – surrounds the entire muscle

Each skeletal muscle fiber is a single cylindrical muscle cell. An individual skeletal muscle may be made up of hundreds, or even thousands, of muscle fibers bundled together and wrapped in a connective tissue covering. Each muscle is surrounded by a connective tissue sheath called the epimysium. Fascia, connective tissue outside the epimysium, surrounds and separates the muscles. Portions of the epimysium project inward to divide the muscle into compartments. Each compartment contains a bundle of muscle fibers. Each bundle of muscle fiber is called a fasciculus and is surrounded by a layer of connective tissue called the perimysium. Within the fasciculus, each individual muscle cell, called a muscle fiber, is surrounded by connective tissue called the endomysium.

Skeletal muscle cells (fibers), like other body cells, are soft and fragile. The connective tissue covering furnish support and protection for the delicate cells and allow them to withstand the forces of contraction. The coverings also provide pathways for the passage of blood vessels and nerves.

Commonly, the epimysium, perimysium, and endomysium extend beyond the fleshy part of the muscle, the belly or gaster, to form a thick ropelike tendon or a broad, flat sheet-like aponeurosis. The tendon and aponeurosis form indirect attachments from muscles to the periosteum of bones or to the connective tissue of other muscles. Typically a muscle spans a joint and is attached to bones by tendons at both ends. One of the bones remains relatively fixed or stable while the other end moves as a result of muscle contraction.

Skeletal muscles have an abundant supply of blood vessels and nerves. This is directly related to the primary function of skeletal muscle, contraction. Before a skeletal muscle fiber can contract, it has to receive an impulse from a nerve cell. Generally, an artery and at least one vein accompany each nerve that penetrates the epimysium of a skeletal muscle. Branches of the nerve and blood vessels follow the connective tissue components of the muscle of a nerve cell and with one or more minute blood vessels called capillaries.

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