Скачать или смотреть Managing Weight Gain from Psychiatric Medications with Dr. Michael Cummings

00:00:00 - Introduction: Dr. Michael Cummings on Psychopharmacology and Weight Gain
00:01:20 - A Refreshing Perspective in Psychiatry
00:03:00 - The Obesity Epidemic in Psychiatric Populations
00:05:00 - GLP-1 Agonists: A New Tool for Weight Loss and Addiction
00:07:30 - Risks of GLP-1s
00:10:00 - GLP-1 Effects on Reward Systems and Behavior
00:13:00 - Motivation Loss and Hypothalamic Regulation
00:16:00 - Challenges in Sustainable Lifestyle Change
00:18:00 - Medications That Cause Significant Weight Gain
00:20:00 - Clozapine and Olanzapine: Mechanisms of Weight Gain
00:22:30 - Histamine, Serotonin, and Insulin Effects on Metabolism
00:25:00 - The Impact of Antipsychotics on Leptin and Ghrelin
00:28:00 - Insulin Resistance, Obesity, and Mental Health
00:31:00 - Glucose Dysregulation in Psychiatry Patients
00:33:30 - The Brain's Fight Against Modern Food Environments
00:36:00 - Risperidone, Prolactin, and Long-Term Health Risks
00:39:00 - Managing Hyperprolactinemia
00:42:00 - Clinical Guidelines for Addressing Elevated Prolactin
00:45:00 - Mirtazapine and Other Antidepressants That Cause Weight Gain
00:47:30 - Importance of Weighing Patients in Psychiatry Practice
00:50:00 - Challenges and Successes of Lifestyle Interventions
00:52:00 - Metformin and Early Intervention for Weight Management
00:54:30 - Managing Clozapine-Related Weight Gain
00:57:00 - GLP-1s in Schizophrenia
01:00:00 - Public Health Systems and GLP-1 Negotiations
01:02:00 - Considerations When Switching Antipsychotics
01:04:00 - New Antipsychotic Options: Xanomeleine and Future Prospects
01:06:30 - Final Reflections: Building Healthy Habits for Providers and Patients


In this episode, Dr. David Puder sits down with renowned psychopharmacologist Dr. Michael Cummings to explore a critical issue in psychiatric care—managing weight gain caused by psychiatric medications. Antipsychotic drugs like clozapine and olanzapine can lead to serious metabolic challenges, including obesity and metabolic syndrome. Dr. Cummings breaks down the science behind drug-induced weight gain, focusing on the role of GLP-1 agonists, a promising class of medications that can help combat these side effects.

If you're a mental health professional, patient, or someone interested in the intersection of psychiatry and physical health, this episode is packed with practical strategies to manage weight gain, improve metabolic health, and navigate the complexities of long-term medication use. Tune in to learn how cutting-edge treatments and lifestyle changes can help improve outcomes for those impacted by psychiatric medications.

Topics Covered:

-The connection between psychiatric medications and weight gain
-How GLP-1 agonists can reverse obesity in psychiatric patients
-Practical tips for managing weight gain: diet, exercise, and pharmacological interventions
The impact of antipsychotics like clozapine and olanzapine on metabolic health
-Long-term considerations for patients using GLP-1s

Subscribe for more in-depth discussions on mental health, psychiatry, and overall wellness.

0:00 Intro
2:55 GLP-1 Agonists in Psychiatry and Weight Management
6:55 Challenges and Caveats of GLP-1 Agonist
18:02 Psychiatric Medication and Weight Gain
18:47 Clozapine and Olanzapine and Weight Gain
24:53 Insulin and Weight Gain
30:41 Risperidone: Influence on Weight Gain and Prolactin
39:52 Assessing Side Effects and the Importance of Early Intervention
44:34 Other Psychotropics Known to Cause Weight Gain
46:03 Multimodal Approaches to Address Medication-induced Weight Gain
54:50 New Medications Being Studied
56:46 Medication Changes and the Risk of Decompensation
59:41 Topiramate for Weight Loss: Cognitive Impairments, Renal Risks, and Patient Monitoring
01:03:46 Integrating Strength Training and Psychiatry: Building Habits for Providers and Patients
01:06:47 Building Lifelong Healthy Eating Habits: Small Dietary Changes for Sustainable Health

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