Скачать или смотреть Ischemic stroke medication beliefs, adherence and perception - Video abstract [ID 235107]

Video abstract of an original research "The Association Among Medication Beliefs, Perception of Illness and Medication Adherence in Ischemic Stroke Patients: A Cross-Sectional Study in China” published in the open access journal Patient Preference and Adherence by Suebsarn Ruksakulpiwat, Zhaojun Liu, Shihong Yue et al.
Purpose: To examine the association and the mediating effect among medication beliefs,
perception of illness, and medication adherence in ischemic stroke patients.
Patients and Methods: This is a cross-sectional study, 306 ischemic stroke patients
recruited from The Second Affiliated Hospital of Harbin Medical University, China between
June 2018 and October 2018. The Beliefs about Medications Questionnaire (BMQ) was used
to assess a patient’s beliefs about medication. The Brief Illness Perceptions Questionnaire
(BIPQ) was used to rapidly determine the cognitive and emotional representation of ischemic
stroke. Self-reported adherence was assessed using the Medication Adherence Report Scale
(MARS). Logistic regression analysis, Pearson correlations, and mediation analysis were
used to evaluate the association and mediating effects among medication beliefs, perception
of illness, and medication adherence.
Results: Overall, 220 (65.48%) participants were non-adherent to their ischemic stroke medications.
Non-adherent patients had greater stroke severity (p = 0.031) compared to adherent patients.
After adjusting for demographic characteristics, specific concern (odds ratio [OR]: 0.652, 95%
confidence interval [CI]: 0.431 to 0.987, p-value [P] = 0.043), and the perception of illness (overall
score) (OR: 0.964, 95% CI: 0.944 to 0.985, P = 0.001) were significantly associated with
medication adherence in ischemic stroke patients. The mediation analysis showed the significant
indirect effects of specific concern, general overuse, and general harm. It suggested that some
impacts of medication beliefs have been mediated on medication adherence.
Conclusion: Perceived concern about adverse effects of medicines and perception of illness
have an influential impact on self-reported medication adherence in ischemic stroke patients. To
enhance adherence, patients’ beliefs about medication and perceptions of their disease should be
reconsidered. Future work should investigate interventions to influence patient adherence by
addressing concerns about their ischemic stroke medications and the perception of the disease.

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