Development of Eye (Primary, Secondary and Tertiary Vitreous) and its Disorders

#Vitreous embryology and anomalies

The embryology of the vitreous is often overlooked.Embryologically, the vitreous humor originates primarily from the mesenchyme of the optic cup and the neural crest cells. As the eye develops, these cells undergo complex differentiation and organization to form the gel-like substance known as the vitreous humor. This process involves the secretion of various extracellular matrix components, such as collagen fibrils and hyaluronic acid, which give the vitreous its unique properties of transparency and gel-like consistency.
The vitreous is not immune to anomalies and developmental disorders. Anomalies in vitreous embryology can lead to a spectrum of clinical manifestations, ranging from benign to vision-threatening conditions. These anomalies may include persistent fetal vasculature (PFV), also known as persistent hyperplastic primary vitreous (PHPV), where remnants of the fetal vasculature fail to regress properly, causing tractional forces on the retina and potential vision loss.
Topics discussed :-
What is primary vitreous?
What is secondary vitreous ?
What is tertiary vitreous?
What are their origins?
what are anomalies of development?
What is tunica vasculosa lentis?
What is persistent hyperplastic primary vitreous?
what is anterior v/s posterior PHPV
What is bergmeister papillae?
What is mittendorf dot ?
what is persistent pupillary membrane?

link for development of lens and optic vesicle:    • DEVELOPMENT OF EYE( optic vesicle and...  

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