Olink Podcast | Ep 21 Complementarity of Mass Spec and PEA

Welcome to the Olink® Proteomics in Proximity podcast!
Below are some useful resources mentioned in this episode:

UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-mor...

UKB-PPP online resources developed by Nick Lehner and Maria Wörheide
https://metabolomips.org/ukbbpgwas/

Metabolomics and Proteomics Core in Munich:
https://www.helmholtz-munich.de/en/co...
https://www.helmholtz-munich.de/core-...
[email protected]
ClinspectM (https://clinspect-m.mscoresys.de/) consortium in the Munich area dedicated to move proteomics forward to clinical application
More joint initiatives towards Germany-wide benchmarking and standardized processes are in the making, follow the news on https://www.mscoresys.de/

Research articles
Sun, B.B., Chiou, J., Traylor, M. et al. Plasma proteomic associations with genetics and health in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06592-6
https://www.nature.com/articles/s4158...
Petrera A, von Toerne C, Behlr J, et al. Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. (2020) Journal of Proteome Research
https://pubs.acs.org/doi/pdf/10.1021/...

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.
Kardell O, von Toerne C, Merl-Pham J, König AC, Blindert M, Barth TK, Mergner J, Ludwig C, Tüshaus J, Eckert S, Müller SA, Breimann S, Giesbertz P, Bernhardt AM, Schweizer L, Albrecht V, Teupser D, Imhof A, Kuster B, Lichtenthaler SF, Mann M, Cox J, Hauck SM. J Proteome Res. 2024 Jan 5;23(1):117-129. doi: 10.1021/acs.jproteome.3c00473. Epub 2023 Nov 28. PMID: 38015820
https://pubs.acs.org/doi/10.1021/acs....

Olink tools and software
Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/e...
Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: https://olink.com/products-services/e...

Subscribe to the podcast on your favorite player or app:
Apple Podcasts: https://apple.co/3T0YbSm

Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...

Google Podcasts: https://podcasts.google.com/feed/aHR0...

Amazon Music: https://music.amazon.com/podcasts/d97...

Podcast Addict: https://podcastaddict.com/podcast/409...

Deezer: https://www.deezer.com/show/5178787

Player FM: https://player.fm/series/series-3396598

In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: https://bit.ly/3Rt7YiY

For any questions regarding information Olink Proteomics, please email us at [email protected] or visit our website: https://www.olink.com/

Interested in a specific podcast topic or guest? Reach out to us at PIP at olink.com

WHAT IS PROTEOMICS IN PROXIMITY?
Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Cindy Lawley and Sarantis Chlamydas.