Insulin Signal Transduction Pathway👨‍⚕️

#drnajeeb #pharmacology #RestingMembrane #neurology

Resting Membrane Potential | Neurology | Dr Najeeb👨‍⚕️

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

00:00:00 Introduction
00:00:42 Insulin
00:01:18 Function Of Insulin
00:04:56 Parts/Structures Of Insulin
00:10:07 Role Of Intrinsic Enzyme
00:14:33 Mechanism Of Action Of Insulin
00:25:43 Role Of Pi3k
00:28:26 Review
00:30:32 Important Enzymes
00:33:55 Akt Protein/P.K.B And Pdk
00:36:37 Role Of Glut 4 Channels In Glucose Uptake
00:40:00 Pi3k Pathway
00:41:56 Synthesis Of Glycogen
00:46:14 Metabolic Functions
00:48:18 Catabolic Enzymes
00:49:47 Effect On Protein And Lipid
00:51:20 M Tor
00:52:00 Review
00:58:05 What Is Proptosis?
01:02:04 Review

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The resting potential of the nerve cell is because of the differences of ionic concentration, which are maintained on the two sides of the membrane by metabolic processes. If undisturbed, the system remains in a steady state, but it is not in thermodynamic equilibrium. When a molecule is dissociated into ions in a solution, and the latter is divided by a semipermeable membrane into two compartments with unequal ionic concentrations, then an electric potential difference exists between the compartments. This chapter discusses how a relationship between potential and concentration differences at equilibrium can be derived. It discusses the exchange of ions across a membrane as a more accurate derivation of the resting potential must take into account that several species are involved in ion exchange across the membranes and as it must include the different permeabilities of the membrane to the various ions.
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