Скачать или смотреть Treating Depression: Practical Tips & Pearls for Anti-Depressant Medications | Psychofarm Podcast

This episode explores the medications used in treating depression, highlighting the importance of personalized approaches to care. Learn about effective strategies for managing depression, from optimizing medications to incorporating lifestyle and therapy interventions for better mental health outcomes.
💡Anti-depressant Course: https://www.psycho.farm/antidepressan...
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00:00 Intro: Winter Blues, Sunlight & Introductions
00:03:28 Depression as a Symptom & Importance of Correct Diagnosis
00:08:51 First-Line Meds for MDD: SSRIs (Zoloft/Lexapro) & Others (Wellbutrin/Mirtazapine)
00:12:37 When First Med Fails: Dose, Switch vs. Augment (STAR*D)
00:16:45 Practical Dosing & Titration Strategies for SSRIs
00:21:38 Using Scales (PHQ-9) to Track Symptoms & Guide Treatment
00:25:11 SNRIs: When to Use, Efficacy & Side Effects (esp. Effexor Withdrawal)
00:29:24 Deeper Dive: Comparing SSRIs (Prozac, Paxil, Luvox, Celexa)
00:36:15 Augmentation Strategies: Sleepers, Buspar, Antipsychotics
00:43:36 CRUCIAL: Beyond Meds - Lifestyle, Therapy & Psychoeducation
00:47:07 Older Meds (TCAs/MAOIs), Stimulants & Other Options (TMS/ECT)
00:55:45 Managing Common Side Effects (Weight, Sexual, GI, Bruxism)
01:02:25 Duration of Treatment, Stopping Meds & Relapse Risk
01:05:55 Addressing Stigma & Why the Therapeutic Relationship Matters
01:10:20 Outro & Shout-outs


Depression is a complex and multifaceted condition that requires careful diagnosis and a tailored approach to treatment. In this episode, we focus on the key principles of managing depression effectively, addressing common pitfalls in diagnosis and exploring evidence-based strategies for treatment. You’ll learn why depression is not a one-size-fits-all diagnosis, with insights into how symptoms can arise from conditions such as bipolar disorder, trauma, or personality disorders.

Once major depressive disorder (MDD) is confirmed, selecting the right treatment is critical. We’ll break down the first-line options, including SSRIs like Sertraline and Escitalopram, and discuss alternatives such as Bupropion and Mirtazapine for specific patient needs. You’ll also discover the importance of reaching therapeutic doses before considering a medication switch or augmentation.

For partial responders, we’ll explore augmentation strategies, including the use of Bupropion, Mirtazapine, or second-generation antipsychotics like Aripiprazole. We’ll also highlight the importance of addressing side effects like weight gain, sexual dysfunction, and bruxism to improve adherence and outcomes. Beyond medications, we emphasize the critical role of lifestyle changes, behavioral activation, and psychotherapy in fostering sustained recovery.

This episode also covers advanced treatments such as Transcranial Magnetic Stimulation (TMS) and Electroconvulsive Therapy (ECT), shedding light on their efficacy and safety profiles for treatment-resistant cases. Throughout the discussion, we underline the importance of the therapeutic relationship, shared decision-making, and patient-centered care in achieving long-term success.

Whether you’re a clinician seeking actionable advice or someone looking to better understand depression and its treatment, this episode provides a comprehensive guide to managing this challenging condition. Join us to gain a deeper understanding of how to navigate the complexities of depression and empower patients on their journey to recovery.