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Dermal Filler is a gel of hyaluronic acid (HA) generated by streptococcus species of bacteria, and chemically cross linked with a moisture-absorbing gel such as BDDE (1,4-butanediol diglycidyl ether). When crosslinked HA and unreacted BDDE degrade, they break down into harmless byproducts that are identical to substances already found in the skin.
You may experience a slight burning sensation during injections, although numbing cream is always used to lessen this. The procedure (depending on areas treated) takes typically 20-40 minutes. Results last from 6 to 12 months for more "liquid" fillers such as Belotero and Restylane, and 18 to 24 months for more viscous (thicker) material such as Juvederm Voluma.

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