Nutrition Professor: How inflammation could age you | Philip Calder

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Inflammation is a complicated topic. Short-term inflammation plays an essential role in fighting infections and healing injuries. But too much inflammation can be a catalyst for chronic ailments, like heart disease, type 2 diabetes, autoimmune disorders, rheumatoid arthritis, and obesity.

What we eat can influence our inflammatory responses and contribute to chronic, low-grade inflammation.

In today’s episode, Prof. Philip Calder helps us understand the science behind inflammation, how it impacts our health and what food has to do with it.

Philip is head of the School of Human Development and Health, as well as a Professor of Nutritional Immunology, in the Faculty of Medicine at the University of Southampton. He’s also an internationally recognised researcher on the metabolism and functionality of fatty acids. His work focuses on the roles of omega-3 fatty acids and the influence of diet and nutrients on immune and inflammatory responses.

Timecodes:
00:00 Introduction
01:10 Quickfire questions
03:00 The role of inflammation in immunity
05:40 Chronic inflammation and disease
08:49 How to measure inflammation
10:14 Should you worry about low-grade inflammation?
12:54 What causes blood vessel inflammation?
16:03 What creates the narrowing of blood vessels?
18:21 How inflammation can cause blood clots, heart attacks and strokes
20:13 Inflammation and aging
22:41 Inflammation and lifestyle factors
26:11 Obesity and inflammation
29:48 Muscle loss and inflammation (sarcopenia)
31:56 The impact of meals, sugar and fats on inflammation
36:04 Impact of diet inflammation
37:11 Why we all respond to food differently
42:25 What are omega-3s?
43:45 Anti-inflammatory foods
46:08 Health benefits of omega-3 fatty acids
48:24 Challenges with farmed salmon

Studies relevant to today's episode:
Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?, published in British Journal of Clinical Pharmacology
Link: https://bpspubs.onlinelibrary.wiley.c...

Omega-6 fatty acids and inflammation, published in PLEFA
Link: https://www.plefa.com/article/S0952-3...

Omega-3 Fatty Acids and Inflammatory Processes, published in Nutrients.
Link: https://www.mdpi.com/2072-6643/2/3/355

Health relevance of the modification of low-grade inflammation in ageing and the role of nutrition, published in Ageing Research Reviews
Link: https://www.sciencedirect.com/science...

Books:
Every Body Should Know This by Dr Federica Amati: https://amzn.to/4blJsLg
Food For Life by Prof. Tim Spector: https://amzn.to/4amZinu

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Episode transcripts are available: https://zoe.com/learn/category/podcasts