Скачать или смотреть Pyaemia definition causes clinical features investigation treatment

PYAEMIA

Presence of multiplying bacteria in blood as emboli which spread and lodge in different organs in the body like liver,lungs, kidneys, spleen, brain causing pyaemic abscess.
This
may lead to multi organ dysfunction syndrome (MODS).
It
may endanger life if not treated properly.

Clinical features :

Fever with chills and rigors
Jaundice, oliguria, drowsiness
Hypotension, peripheral circulatory collapse and later coma with MODS.

Common Causes :

Urinary infection (most common).
Biliary tract infection.
Lower respiratory tract infection.
Abdominal sepsis of any cause.
Sepsis in diabetics and immunosuppressed individuals like HIV, steroid therapy.

Investigations :

Total leucocyte count, platelet count.
C reactive protein.
Pus, blood, urine culture depending on need.
Blood urea, serum creatinine.
Liver function tests, prothrombin time.
Chest X-ray, USG abdomen.
CT chest/abdomen/brain as needed.
Arterial blood gas analysis if needed.

Treatment :

Monitoring of vital parameters.
Antibiotics (ceftazidime, cefoperazone, ceftriaxone sodium).
IV fluids, maintenance of urine output.
Hydrocortisone—200–600 mg IV.
Blood and plasma transfusion.
Nasal oxygen, ventilator support, monitoring of pulmonary function.