Скачать или смотреть ARC-20: casdatifan monotherapy in pre-treated clear cell renal cell carcinoma

Bradley McGregor, MD, Dana-Farber Cancer Institute, Boston, MA, discusses results from the Phase I ARC-20 trial (NCT05536141) of casdatifan monotherapy in patients with clear cell renal cell carcinoma (ccRCC) previously treated with PD-(L)1 and VEGFR-TKI therapies. Casdatifan showed promising activity across all risk groups, with manageable safety signals, including anemia and hypoxia. Based on these findings, casdatifan will be investigated in combination with cabozantinib in the Phase III PEAK-1 trial. This interview took place at the ASCO GU Cancers Symposium 2025 in San Francisco, CA.

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