AHA 23: ECLS-SHOCK: Impact of Cardiac Arrest on the Efficacy of ECLS Patients

We are joined on-site by Prof Uwe Zeymer (Klinikum Ludwigshafen, Ludwigshafen, DE) to discuss the findings from a sub-analysis of the ECLS-SHOCK trial.

This sub-analysis investigates the impact of cardiac arrest before randomisation on the efficacy of ECLS in patients with infarct-related cardiogenic shock. Investigators enrolled 420 patients with acute MI and cardiogenic shock across 41 centers. The primary outcome was 30-day mortality.

Investigators reached 49% mortality in the control group, however there was no reduction in mortality with implantation of a VA-ECMO device at 47.8%. Bleeding and vascular complications were higher regardless of whether patients had cardiac arrest before randomisation.

Interview Questions:
-What is the reasoning behind this sub-analysis?
-What was the patient population and study design?
-What were your key findings?
-What are your take-home messages?
-What further study is needed, and what are the next steps?

Recorded on-site at AHA Scientific Sessions 2023, Philadelphia.

Support: This is an independent interview conducted by Radcliffe Cardiology.

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