Equivalent Circuit Model Of The Neuron Explained (Capacitance, Resistance, Driving force) | Clip

Welcome to Science With Tal!

In this clip of the Signal Propagation in the Neuron video, we will discuss how we can model the neuron as an electrical circuit. We will discuss each analog (resistance, capacitance, voltage, current, driving force) and I’ll give further intuition on how to understand these components of the model. You will see here and in the comment section the time stamps associated with each topic that I’ve covered.

Note that the graphs are not up to scale but the general shapes of the curves reflect the true behaviors of the variables in question.

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Timestamps

0:00 Introduction
0:22 Motivation behind the model
1:15 Membrane capacitance & resistance
3:00 Driving force derivation
5:40 IV curve using I = G(V-E)
7:19 Building the circuit
8:55 Derivation of the equivalent circuit model equation
10:15 Note on passive and active signals
12:00 Alternative equivalent circuit model
14:15 Conclusion

Resources used

Here is a list of the resources that I’ve used to produce this video. (Author: title resource)

Dale Purves: Neuroscience (6th edition)
Eric Kandel: Principles of neural science (6th edition)
Alan Hodgkin & Andrew Huxley: A quantitative description of membrane current and its application to conduction and excitation in nerve
Alan Hodgkin & William Albert Hugh Rushton: The electrical constants of a crustacean nerve fibre.

To have more information on these resources, you can refer to the conclusion section where a more formal citation is provided.

Video credits

Writing: Tal Klimenko
Voice: Tal Klimenko
Animations: Tal Klimenko
Drawings: Tal Klimenko
Editing: Tal Klimenko
Introductory jingle: Thierry Du Sablond
Conclusion music: lukrembo - jay (   • lukrembo - jay (royalty free vlog music)  )