Скачать или смотреть An update on new treatments and clinical trials for genetic therapies - Prof Andreas Brunklaus

In this powerful talk, Prof Andreas Brunklaus explores the cutting edge of treatment for rare genetic epilepsies, with a focus on Dravet syndrome and SCN1A-related disorders. He outlines the rapid evolution from gene discovery to disease-modifying therapies, including antisense oligonucleotides (ASOs) and gene regulation techniques.

Learn how international collaborations are driving early diagnosis, predictive tools, and natural history studies essential for the next generation of precision medicine. Prof Brunklaus also shares compelling before-and-after videos of treatment effects and discusses the future of clinical trials—including the challenges of sham-controlled studies and ethical trial design.

Highlights include:

The SCN1A spectrum: from mild to severe epilepsy
Predictive algorithms to guide early intervention
Updates on ASO trials and gene therapy strategies
The role of natural history data in advancing care
Real-world functional improvements beyond seizure control

Whether you're a clinician, researcher, or family advocate, this is a must-watch for understanding the evolving landscape of genetic epilepsy treatment.