Скачать или смотреть Doc Edge presents “Using gene genealogies to understand complex traits” - GGA Seminar Series

On Monday January 29, the Genetics and Genomics Academy hosted Doc Edge, assistant professor of quantitative and computational biology at University of Southern California, to present “Using gene genealogies to understand complex traits.”

Abstract -
"Ancestral recombination graphs (ARGs) use trees to relate variation in a sample of genomes to the genealogical sources of that variation. Recent computational advances have enabled the largest-scale ARG estimates to date, raising the possibility of ARG-based approaches to any data analysis that takes genetic variation as input. In this talk, I will discuss ways in which estimated ARGs can interface with the study of complex traits. These projects highlight the ARG—and the marginal trees it encodes—as a common language for relating evolutionary and statistical genetics."