Digoxin - Mechanism of Action

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Video Summary:
This is video on digoxin mechanism of action.
Notes from the video.
- Digoxin is a cardiac glycoside
- It is used in heart failure
- It inhibits Na-K ATPase pump and thereby increases intracellular Ca after sequence of events. Increased Ca helps cardiac myocyte contract better.
- Digoxin and K competes with other for same binding site on Na-K ATPase.
- In case of hypokalaemia there are chances of digoxin toxicity and in hyperkalemia digoxin effect may reduce.

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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.