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Building the Blueprint to Block HIV

The End of Daily Pills? How Lenacapavir & Capsid Science Block HIV 🧬

Is the era of daily pills for HIV prevention coming to an end? 🌍 In this video, we break down the revolutionary science behind Lenacapavir, the new injectable PrEP that offers protection for six months at a time.

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For years, preventing HIV meant taking a pill every single day. While effective, this method faces huge hurdles: stigma, unreliable access, and pill fatigue. But a breakthrough collaboration between Wesley Sundquist (University of Utah) and Tomas Cihlar (Gilead Sciences) has changed the game entirely.

👇 In this video, you will learn:
The Capsid Blueprint: How Sundquist’s 30 years of research revealed the HIV capsid (the virus's outer shell) is not just a container, but a "vulnerable" cone-shaped engine essential for infection.

The Mechanism: How Lenacapavir works by deforming this capsid, making it too fragile to protect the viral genome or enter the cell nucleus.

The "100% Efficacy" Trial: A look at the groundbreaking clinical trials in South Africa where women receiving the injection had zero new infections—a result experts like Linda-Gail Bekker had "never seen before."

Global Recognition: Why this discovery landed Sundquist and Cihlar on the Time 100 list and won the AAAS Breakthrough of the Year Award.

This is one of the most significant advancements in HIV prevention history, bringing us closer to a vaccine-level of protection with almost no effort from the user.

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Disclaimer:

Medical Disclaimer: The content in this video and description is for educational and informational purposes only. It is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment options. Never disregard professional medical advice or delay in seeking it because of something you have heard in this video.

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