Скачать или смотреть Psychiatric Symptoms or Metabolic Disorder? The Overlooked Role of Folate Pathways

Depression, anxiety, hallucinations, unusual behavior, or worsening memory are often assumed to be psychiatric. Sometimes that’s true—and mental health care can be essential. But there’s an overlooked possibility: these symptoms may reflect disrupted metabolic pathways that affect brain function. In medicine, this can fall under inborn errors of metabolism (IEM) and genetic metabolic brain disorders (GMBDs), which can present with psychiatric features and be mistaken for primary psychiatric illness.

Folate-related metabolic pathway abnormalities can also produce symptoms that look psychiatric—and some are treatable. Just as important: folate isn’t one single substance. It includes different molecular forms, and different disorders involve different “bottlenecks,” so the appropriate strategy can vary.
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