Скачать или смотреть All Things Ketones, How to Boost Cognition, Sardine Fasting, Diet Rules, & More — Dr. Dom D’Agostino

Dr. Dominic D’Agostino is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.

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[00:00] Start
[00:42] Why I'm interested in ketogenic strategies for neurodegenerative prevention.
[02:17] Mary and Steve Newport's ketone-linked temporary cognitive improvements.
[04:31] A mechanisms overview for Alzheimer's/dementia.
[07:45] The immune system as longevity's "fifth horseman" — and why metabolic control is key.
[08:26] How to measure ketones and GKI.
[09:26] Fasting vs. ketogenic diet.
[10:48] There's nothing fishy about sardine fasting.
[15:05] My hiatal hernia discovery and increased cancer risk concerns.
[16:46] HSCRP as a superior biomarker to LDL for cardiovascular risk.
[18:39] Glucose tolerance testing revelations and CGM importance.
[24:12] Upgrading the metabolic machinery through keto without getting bored.
[27:43] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.
[31:43] Dom's day-to-day diet regimen.
[37:29] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.
[41:50] Supplementing for sleep disruption while fasting.
[45:20] Why Dom doesn't have misgivings about melatonin.
[46:09] Shingles prevention through fasting protocols.
[46:32] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.
[50:15] Dom at 50-something: Current meal timing and composition.
[53:35] Blue zone observations: Greek and Sardinian longevity habits.
[54:39] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.
[01:01:49] Ketone metabolic therapy for cancer.
[01:04:54] The metabolic psychiatry revolution.
[01:08:49] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.
[01:15:10] Metformin vs. berberine.
[01:18:29] The low-dose neuroprotective potential of GLP-1 drugs.
[01:21:44] NAD research: MIB-626 and stabilized forms for mitochondrial health.
[01:26:38] Idebenone, CoQ10, and the Deanna protocol for ALS.
[01:28:55] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.
[01:31:36] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.