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Controlling Stereocenters in Organic Synthesis

1. Use chiral reagents or catalysts
2. Bias reactions toward one isomer
3. Attach chiral auxiliaries temporarily
4. Remove auxiliaries after directing outcome
5. Start from chiral pool molecules
6. Prefer asymmetric methods over resolution

Common Stereochemistry Mistakes and Fixes

1. Assuming one catalyst fits all reactions
2. Ignoring stereochemistry in early steps
3. Choosing resolution before asymmetric methods

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