At our February Pain Science Lecture, current pain fellow Alice Li discussed the benefits of physical exercise for chronic pain treatment and how to integrate movement into treatment plans.
A Stanford-trained physician and pain fellow, Dr. Li believes that "Movement is Life." She blends her clinical expertise and passion for dance to help patients manage painful conditions.
0:00 – Introduction to chronic pain and exercise
0:17 – Distinguishing chronic vs. acute pain
0:43 – Overview: exercise as treatment, mechanisms, types, evidence, side effects, recommendations
1:32 – Exercise types ranked for pain relief (Pilates, mind-body, core, strength, combined, stretching, McKenzie, aerobic)
2:32 – Physical Activity Guidelines for Americans: children/adolescents benefits
5:02 – Adults and older adults: mortality, cardiovascular health, diabetes, cancer, cognition, dementia, sleep, bone health, quality of life
8:00 – Recommended exercise: 150 min/week moderate aerobic + 2 days muscle strengthening
8:36 – Definition of chronic pain and its relevance to exercise
11:01 – Fear-avoidance behavior and central sensitization explained
14:03 – Mechanisms: anti-inflammatory effects, exercise-induced analgesia, endocannabinoids, endogenous opioids, neurotransmitter modulation
17:17 – Cognitive and psychological benefits: reduced catastrophizing, improved self-efficacy
19:10 – Exercise categories: endurance, strength, HIIT, dynamic flexibility, mixed strength/aerobic, functional fitness
23:02 – Key principles: consistency, pacing, enjoyment, balance
25:28 – Physical therapy: maximize at-home exercises, consider aquatherapy
28:42 – Start slow, read your body, embrace guidance and supervision
30:30 – Multidisciplinary support: physical therapist, clinical exercise physiologist, pain psychology, primary care, pain physician
32:40 – Adverse effects: physical and emotional stress, potential flares, temporary muscle soreness, rare serious events
36:34 – Evidence overview: 381 studies, 37,000 participants; small-to-moderate effect sizes; generally favorable outcomes, minimal risk
39:20 – Exercise as part of multimodal chronic pain treatment: cardiovascular fitness, healthy weight, well-being, reduced disability risk
40:11 – Exercise prescription: mode, intensity, duration, frequency; focus on cardiovascular fitness, strength, balance, flexibility
Stanford Division of Pain Medicine
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