Скачать или смотреть GABA - The Inhibitory Neurotransmitter (+ Alcohol in the Brain) (Level 3 - Advanced)

Explains how GABA (and GABA receptors), the brain's main inhibitory neurotransmitter works at the level of synapses, as well as the role of inhibition in the brain, how certain drugs affect the GABAa receptor (such as alcohol, barbiturates, and benzodiazepines), and how alcohol effects various brain regions.

If you want shorter, less technical explanations of this topic, check out my other videos:
Level 1 (30 seconds):    • GABA - The Inhibitory Neurotransmitte...  
Level 2 (16 mins):    • GABA - The Inhibitory Neurotransmitte...  

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Chapters:
00:00 Why is your brain not constantly having seizures?
01:40 The answer? GABA inhibition
02:19 Me, this channel, this introduciton to neuroscience series.
03:48 I also release less technical, less sciencey videos
04:24 GABA is the brain's main inhibitory neurotransmitter
05:11 GABA is used commonly throughout the brain
06:03 GABA's functions
07:36 The role of inhibition in the brain: the neuronal brakes.
10:00 Review of how glutamate affects neurons
10:36 Terminology: EPSP and IPSP (excitation and inhibition)
12:13 How GABA affects its receptors
12:29 The GABAa ionotropic receptor mechanism: chlorine influx
14:40 The GABAb metabotropic receptor mechanism: potassium efflux
16:42 A neuron weighs up thousands of inputs to decide whether it will fire.
18:42 The closer to the axon hillock, the stronger the inhibitory input.
21:17 Alcohol, barbiturates, and benzodiazepines bind to the GABAa receptor
23:00 Why do these drugs have different effects?
24:58 Some ways that alcohol affects the brain
30:35 Please like, comment, and subscribe. Thank you!!

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Sources and Recommended Readings:

Kandel, E. R., Koester, J. D., Mack, S. H., & Siegelbaum, S. A. (2021). 13 Synaptic Integration in the Central Nervous System. In Principles of neural science (6th ed., pp. 277–287). essay, McGraw-Hill.

Banich, M. T., & Compton, R. J. (2018). Cognitive neuroscience. Chapter 1: Introduction to the Nervous system. Cambridge University Press.

Sullivan, E. V., Harris, R. A., & Pfefferbaum, A. (2010). Alcohol's effects on brain and behavior. Alcohol Research & Health.

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Music:
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