DMT 🧠 ¿El neurotransmisor de la conciencia?

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⌚ ÍNDICE:
0:00 Introducción
2:00 Historia
3:30 DMT endógeno
4:47 Efectos
6:11 Mecanismo de acción
7:31 DMT durante el nacimiento
9:06 DMT en la experiencia mística
10:51 DMT en la glándula pineal
12:26 DMT en el sueño
14:28 DMT como neurotransmisor
15:56 DMT en experiencias cercanas a la muerte


📚 REFERENCIAS:
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3.- Szára, S. (1956). Dimethyltryptamin: Its metabolism in man; the relation of its psychotic effect to the serotonin metabolism. Experientia, 12(11), 441-442. https://doi.org/10.1007/bf02157378

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7.- Facchini, P. J., Huber‐Allanach, K. L., & Tari, L. W. (2000). Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications. Phytochemistry, 54(2), 121-138. https://doi.org/10.1016/s0031-9422(00...

8.- Barker, S. A. (2018). N, N-Dimethyltryptamine (DMT), an Endogenous Hallucinogen: Past, Present, and Future Research to Determine Its Role and Function. Frontiers In Neuroscience (Online), 12. https://doi.org/10.3389/fnins.2018.00536

9.- Drug scheduling. (1970). DEA. https://www.dea.gov/drug-information/...

10.- Saavedra, J. M., & Axelrod, J. (1972). Psychotomimetic N -Methylated Tryptamines: Formation in Brain in vivo and in vitro. Science, 175(4028), 1365-1366. https://doi.org/10.1126/science.175.4...

11.- Agnes, M. (2023). El hiperespacio del DMT: apuntes cartográficos, étnicos y pararreligiosos. Cáñamo. https://canamo.net/otras-drogas/psico...

12.- Shulgin, A., & Shulgin, A. (1997). TIHKAL: the continuation. Transform press.

13.- Riba, J., Valle, M., Urbano, G., Yritia, M., Morte, A., & Barbanoj, M. J. (2003). Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics. Journal Of Pharmacology And Experimental Therapeutics, 306(1), 73-83. https://doi.org/10.1124/jpet.103.049882

14.- Strassman, R. J., & Qualls, C. (1994). Dose-Response Study of N,N-Dimethyltryptamine in Humans. Archives Of General Psychiatry, 51(2), 85. https://doi.org/10.1001/archpsyc.1994...

15.- Halberstadt, A. L., & Geyer, M. A. (2011). Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens. Neuropharmacology, 61(3), 364-381. https://doi.org/10.1016/j.neuropharm....

16.- Wü, R., Liu, J., & Li, J. (2022). Trace amine-associated receptor 1 and drug abuse. En Advances in pharmacology (pp. 373-401). https://doi.org/10.1016/bs.apha.2021....

17.- Brimson, J. M., Safrany, S. T., & Qassam, H. (2018). Dipentylammonium Binds to the Sigma-1 Receptor and Protects Against Glutamate Toxicity, Attenuates Dopamine Toxicity and Potentiates Neurite Outgrowth in Various Cultured Cell Lines. Neurotoxicity Research, 34(2), 263-272. https://doi.org/10.1007/s12640-018-98...

18.- Ott, J. (1999). Pharmahuasca: Human Pharmacology of Oral DMT Plus Harmine. Journal Of Psychoactive Drugs, 31(2), 171-177. https://doi.org/10.1080/02791072.1999...

19.- Barker, S. A., McIlhenny, E. H., & Strassman, R. J. (2012). A critical review of reports of endogenous psychedelic N, N‐dimethyltryptamines in humans: 1955–2010. Drug Testing And Analysis, 4(7-8), 617-635. https://doi.org/10.1002/dta.422