Скачать или смотреть Dana Lorber: "Evaluation of mesoscale chromatin organization in vivo" - INC

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Dana Lorber is a research associate at the Weizmann Institute of Science, Israel in Professor Volk's laboratory. In one of our webinar sessions, she presented her work: "Evaluation of mesoscale chromatin organization in vivo“. Scientific references of her talk below ↓

To know more about her work: https://www.weizmann.ac.il/molgen/dan...
Twitter: @DanaLorber

This event was organised by:
The International Nucleome Consortium (funded by COST Action CA18127 - funded by the European Union | Horizon Europe).

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References:

1 | Miron E, Oldenkamp R, Brown JM, et al. Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin. Sci Adv. 2020;6(39):eaba8811. Published 2020 Sep 23. doi:10.1126/sciadv.aba8811
2 | Bertero A, Rosa-Garrido M. Three-dimensional chromatin organization in cardiac development and disease. J Mol Cell Cardiol. 2021;151:89-105. doi:10.1016/j.yjmcc.2020.11.008
3 | Dileep V, Tsai LH. Three-dimensional chromatin organization in brain function and dysfunction. Curr Opin Neurobiol. 2021;69:214-221. doi:10.1016/j.conb.2021.04.006
4 | Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. 3D Chromosomal Landscapes in Hematopoiesis and Immunity. Trends Immunol. 2019;40(9):809-824. doi:10.1016/j.it.2019.07.003
5 | Fujita Y. Regulation and dysregulation of spatial chromatin structure in the central nervous system. Anat Sci Int. 2021;96(2):179-186. doi:10.1007/s12565-020-00567-7
6 | Xu J, Ma H, Ma H, et al. Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis. Nat Commun. 2020;11(1):1899. Published 2020 Apr 20. doi:10.1038/s41467-020-15718-7
7 | Razin SV, Gavrilov AA, Iarovaia OV. Modification of Nuclear Compartments and the 3D Genome in the Course of a Viral Infection. Acta Naturae. 2020;12(4):34-46. doi:10.32607/actanaturae.11041
8 | Feng Y, Pauklin S. Revisiting 3D chromatin architecture in cancer development and progression. Nucleic Acids Res. 2020;48(19):10632-10647. doi:10.1093/nar/gkaa747
9 | Kantidze OL, Gurova KV, Studitsky VM, Razin SV. The 3D Genome as a Target for Anticancer Therapy. Trends Mol Med. 2020;26(2):141-149. doi:10.1016/j.molmed.2019.09.011
10 | Dekker J, Belmont AS, Guttman M, et al. The 4D nucleome project [published correction appears in Nature. 2017 Nov 22;:]. Nature. 2017;549(7671):219-226. doi:10.1038/nature23884
11 | Lammerding J, Dahl KN, Discher DE, Kamm RD. Nuclear mechanics and methods. Methods Cell Biol. 2007;83:269-294. doi:10.1016/S0091-679X(07)83011-1
12 | Cremer T, Cremer M, Hübner B, et al. The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments. FEBS Lett. 2015;589(20 Pt A):2931-2943. doi:10.1016/j.febslet.2015.05.037
13 | Cremer M, Brandstetter K, Maiser A, et al. Cohesin depleted cells rebuild functional nuclear compartments after endomitosis. Nat Commun. 2020;11(1):6146. Published 2020 Dec 1. doi:10.1038/s41467-020-19876-6
14 | Lorber D, Rotkopf R, Volk T. A minimal constraint device for imaging nuclei in live Drosophila contractile larval muscles reveals novel nuclear mechanical dynamics. Lab Chip. 2020;20(12):2100-2112. doi:10.1039/d0lc00214c
15 | Amiad-Pavlov D*, Lorber D*, Bajpai G, et al. Live imaging of chromatin distribution reveals novel principles of nuclear architecture and chromatin compartmentalization. Sci Adv. 2021;7(23):eabf6251. Published 2021 Jun 2. doi:10.1126/sciadv.abf6251
16 | Bajpai G, Amiad Pavlov D, Lorber D, Volk T, Safran S. Mesoscale phase separation of chromatin in the nucleus. Elife. 2021;10:e63976. Published 2021 May 4. doi:10.7554/eLife.63976
17 | Lorber D, Volk T. Evaluation of chromatin mesoscale organization. APL Bioeng. 2022;6(1):010902. Published 2022 Jan 12. doi:10.1063/5.0069286
18 | Heo SJ, Thakur S, Chen X, et al. Aberrant chromatin reorganization in cells from diseased fibrous connective tissue in response to altered chemomechanical cues [published online ahead of print, 2022 Aug 22]. Nat Biomed Eng. 2022;10.1038/s41551-022-00910-5. doi:10.1038/s41551-022-00910-5