Скачать или смотреть MLT Question For interview| MLT Question Answer

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Explanation
B cells undergo antigen-independent differentiation in the bone marrow. This is where B cells develop from hematopoietic stem cells and undergo a series of maturation processes, including rearrangement of immunoglobulin genes and expression of surface immunoglobulin receptors. Antigen-independent differentiation in the bone marrow is crucial for the generation of a diverse repertoire of B cells with different antigen specificities. Once mature, B cells leave the bone marrow and migrate to secondary lymphoid organs such as the spleen, lymph nodes, and Peyer's patches, where they can encounter antigens and undergo further activation and differentiation.

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