Скачать или смотреть Why am I gaining weight in my stomach during menopause? Ozempic vs Mounjaro for menopause weight

1. The Menopause-Obesity Link
The transition into menopause often leads to a "metabolic perfect storm." Research indicates that while aging causes general weight gain, menopause specifically dictates where that weight goes.

Visceral Fat Redistribution: Estrogen deficiency shifts fat storage from the hips and thighs (subcutaneous) to the abdomen (visceral). Visceral fat is metabolically active and increases the risk of heart disease and Type 2 diabetes.

Metabolic Slowdown: A decline in estrogen levels is linked to a lower Basal Metabolic Rate (BMR) and reduced fat oxidation.

Sarcopenia: The natural loss of muscle mass during this period further lowers the body’s ability to burn calories at rest.

Hormonal Hunger: Fluctuations in ghrelin (the hunger hormone) and leptin (the satiety hormone) often lead to increased cravings and "emotional eating" triggered by sleep disturbances or mood swings.

2. 2026 Management Strategies
Current clinical guidelines emphasize a "patient-centered" approach that goes beyond the traditional "eat less, move more" mantra.

Medical & Pharmacotherapy
GLP-1 & Dual Agonists: Recent 2025-2026 data shows that medications like Tirzepatide and Semaglutide are highly effective for menopausal women.

Hormone Replacement Therapy (HRT): When used early in the transition, HRT can help mitigate central adiposity and improve insulin sensitivity.

The "Synergy" Effect: New studies suggest that combining HRT with GLP-1 therapy may yield better weight loss outcomes than either treatment alone.

Lifestyle & Nutrition
Resistance Training: This is now considered "non-negotiable." Lifting weights or bodyweight exercises help preserve lean muscle mass, which is critical for maintaining metabolism.

The Mediterranean Pattern: High-fiber, plant-rich diets are favored to support gut health, which has been directly linked to menopausal metabolic health.

Circadian Eating: Aligning food intake with daylight hours to manage insulin spikes, which become more volatile after menopause.