c-ANCA VS p-ANCA (Autoantibodies) | Autoimmune Diseases

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This is different from antinuclear antibodies (ANA) which are antibodies against the nucleus.
Anti-neutrophilic cytoplasmic antibodies (ANCA) have several patterns; the most important two being the cytoplasmic ANCA (c-ANCA) and the perinuclear ANCA (p-ANCA).
Anti-neutrophilic cytoplasmic antibodies (ANCA) are associated with vasculitis, such as granulomatosis with polyangiitis (Wegener granulomatosis), microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), rapidly-progressive glomerulonephritis (RPGN), anti-glomerular basement membrane antibodies (ant-GBM or Goodpasture's syndrome), as well as inflammatory bowel disease-associated. vasculitis.

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In brief, Anti-neutrophilic cytoplasmic antibodies (ANCA) are IgG autoantibodies against the cytoplasm of the neutrophils and monocytes,​ and are associated with vasculitis, but they don't correlate with disease activity or symptoms. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
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