Скачать или смотреть GPCR and arrestin Interactions Analysis to Accelerate Drug Discovery | Protocol Preview

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Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery - a 2 minute Preview of the Experimental Protocol

Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Seongsik Yun, Jong-Ik Hwang, Jae Young Seong
Korea University, Graduate School of Medicine;

GPCR-β-arrestin interactions are an emerging field in GPCR drug discovery. Accurate, precise and easy to set up methods are necessary to monitor such interactions in living systems. We show a structural complementation assay to monitor GPCR-β-arrestin interactions in real time living cells, and it can be extended to any GPCR.

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